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Brain malformations and seizures by impaired chaperonin function of TRiC. Kraft F, Rodriguez-Aliaga P et al. Science. 2024 Nov 1;386(6721):516-525.
Small molecule assembly agonist alters the dynamics of hepatitis B virus core protein dimer and capsid. Kant R, Lee LS et al. J Am Chem Soc. 2024 Oct 23;146(42):28856-28865.
Mechanism of bacterial predation via ixotrophy. Lien YW, Amendola D et al. Science. 2024 Oct 18;386(6719):eadp0614.
Catalytic asymmetric fragmentation of cyclopropanes. Raut RK, Matsutani S et al. Science. 2024 Oct 11;386(6718):225-230.
Ribosomes hibernate on mitochondria during cellular stress. Gemin O, Gluc M et al. Nat Commun. 2024 Oct 8;15(1):8666.
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October 14, 2024
Planned downtime: The Chimera and ChimeraX websites, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable starting Monday, Oct 14 10 AM PDT, continuing throughout the week and potentially the weekend (Oct 14-20).
August 1, 2024
Planned downtime: The Chimera and ChimeraX websites, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable August 1, 3-6 pm PDT.
July 16, 2024
Chimera production release 1.18 is now available. See the release notes for details.
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UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.
We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).
Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.
Feature Highlight
Different conformations and even different proteins can be compared by morphing from one structure to another. Users can specify the method of coordinate interpolation and how many intermediate structures should be generated. The result is displayed in Chimera's trajectory viewer, MD Movie. The morph can then be saved in coordinate form or recorded as an animation. See also: Animation Gallery
(More features...)Gallery Sample
Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.
See also the RBVI holiday card gallery.
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