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The TRPA1 ion channel detects various irritants, including the spicy component of wasabi. The image shows the structure of the human TRPA1 ion channel determined by electron cryo-microscopy (Protein Data Bank entry 3j9p). The four subunits of the tetramer are shown as ribbons in different colors over a dark-to-light gradient background.
The structure is described in the following:
Structure of the TRPA1 ion channel suggests regulatory mechanisms. Paulsen CE, Armache JP, Gao Y, Cheng Y, Julius D. Nature. 2015 Apr 23;520(7548):511-7.© 2015 The Regents of the University of California; all rights reserved.